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What Microbiome Studies Would You Like To See Happen?

We’re about to announce something exciting about some microbiome studies we’re running, but in the meantime I’d love to ask you something.

What microbiome studies would you like to see happen?

I asked this question in our latest newsletter, as well as around the office, and some inspiring and fun replies came in:

– Before and after hand washing, to see how effective it really is
– What’s in that goo that comes out of your eyes in the morning?
– Before and after colonoscopy, to see if the same microbiome returns
Chronic sinusitis, to detect any difference from normal nose/ear passages
– What happens to your gut bacteria during the transition to gluten-free
– Patients with recurrent C. diff infection
Rosacea patients, both skin and gut microbiomes
– The Hashimoto thyroiditis microbiome
Asthma
Rheumatoid arthritis
– Testing the Eat Right For Your Blood Type diet and the probiotics the author recommends for each blood type
– Gut bacteria and sleep deprivation
– The bacteria on money

The 5-second rule: true or false?

Now it’s your turn. Tell us in the comments: what studies do you want to see happen?

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89 Thoughts on “What Microbiome Studies Would You Like To See Happen?”

  • Bill Munro says:

    I would like to see a Ubiome test for kids. My son is liveing with Autism and has had many gut issues over his 13 years and I think with kids on the Spectrum this would be a Huge resource to actually know whether you are addressing the core issues with a non-verbal kid who can’t share whhat he is feeling inside his body in a meaningful way.

    Hoping this is a test that is developed soon!

    Bill Munro

  • Sharm says:

    It would be interesting to see a study done on Hashimoto’s thyroiditis and why when stool testing is done they seem to be missing the same gut flora.

  • Judy says:

    I would love to know if there is a correlation between personality traits and gut bacteria.

  • Joe says:

    It’s been 1 1/2 years since my successful home FMT to reverse my IBS-D. I’d like to see the FDA relax it’s IND requirements somewhat, that make a clinical trial so burdensome for studying the benefits of an FMT for many different diseases. I have been so happy with my successful FMT to reverse my disease. I didn’t get my diary back, that is the only exception. Everything is back, no more ‘flares’ of IBS. I only wish that more people could experience the return to health that I have found. It’s frustrating to have my health back, and yet to see other people struggle with diseases connected with damage to the microbiome, when I know firsthand there is a solution.

    I continue to examine my life for products that may be harmful to my good bacteria, and take steps to eliminate them. We make so many mistakes. We have ignored the elephant in the room, and have approved a long list of products without testing to see whether they harm our good, helpful bacteria. Sadly, there are so many mistakes we make.

    Since finding the best donor is critical to the success of FMTs, and reversing disease, I believe we need 10-fold larger effort to find and recruit the best donors, so our FMT trials will be successful. Dr Colleen Kelly has my observations on which steps we can take to improve success rates. The ideal donor is a crucial step to an FMT.

    Since the average American has already lost 40% of this ecosystem it does make it a challenge to find the best donor. We should also consider this for the treatment aspect. We need this diversity, the greater the diversity, the better our health. Remember too, that many of us carry some bad actors, and that our good bacteria keep these bad ones inline. But, don’t stop there. These bad actors have a role in training our immune system. The concept of implanting just good bacteria does not establish a healthy ecosystem. We don’t want a ‘pine forest plantation’, we want a ‘natural rain forest’. So, I know there are efforts to just implant only good bacteria, but this is not really the right approach.

    Moving forward. I believe our oral microbiome plays an enormous role in the establishment of the connecting microbiomes throughout the intestinal tract. We are, however, disrupting this oral microbiome. We, unwittingly, drink chlorinated water on a daily basis. While it is very important in our water supply for preventing water borne diseases, it is a mistake for us to ingest a product that indiscriminately kills bacteria, inside of us. We have from 600 to 800 species of bacteria in our oral microbiome. What is interesting is that some of these bacteria are anaerobic, the ones that populate 90% of our gut microbiome. I believe there is an important, very natural role being played by the oral microbiome in populating the connecting microbiomes, however we’ve been unwittingly disrupting it.

    What else do we do to the oral microbiome ? Well, let’s think about mouthwash. It kills bacteria. We approved this product for human consumption without having any idea how important the human microbiome is to our health, and that when we kill species of good bacteria and disrupt balances of good vs bad bacteria, we in turn affect our health.
    I suggest that we strongly need to re-evaluate the wisdom of daily using a product that kills bacteria. I believe it disrupts the oral microbiome flora, which in turn has a cascading affect on subsequent microbiomes.

    Let’s think about toothpaste as well. If we read the label, it says,”if more is consumed than is normally used for brushing, call a poison control center immediately”. This should give us pause. We don’t have studies that determine if toothpaste is harmful to our good oral bacteria. Does it disrupt this ecosystem ? I’m not against flossing and brushing, not at all. But, we need to re-think this. First, and foremost, we need to get the added sugars our of diets, they feed the bad bacteria of our oral, and our gut microbiomes. So, when we eliminate this first mistake in our diet (sugar), then perhaps we can better assess the necessity of toothpaste . Our processed foods have added sugars, the trouble is they feed our bad bacteria. Our food producers add them because they compete for our food dollar, yet when we understand the microbiome, it’s
    really an epic mistake.

    Granted, we’ve made good progress in 2016. We’ve banned the foolish practice of adding antibacterials to hand soaps. We’ve also banned low level antibiotics used in animal feed to increase weight gain. This will take affect Jan 1st, 2017. We now need to encourage our medial professionals all across the USA to reduce the number of antibiotics given, when possible. It’s all to clear that antibiotics have a devastating affect on the microbiome. Sure, we need them to save lives. But, we need to reduce use, when possible.

    One last thing, I predict and hope that home fermentation of vegetables and fruits will become commonplace. Sorry for the long post.

  • Rebecca Savastio says:

    I’m really shocked that there is no active study on the microbiome and obesity. I think this should be next on your list.

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