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Your gut has something to
tell you.

Smart, actionable insights
to improve your gut health.

The world’s first sequencing-based clinical microbiome test

With SmartGut, you and your healthcare provider can gain valuable insights to better understand what’s going on inside your gut, then take steps for you to feel better. Using precision sequencing™ technology, SmartGut identifies microbes in your gut that might be affecting your health.

Why SmartGut?

SmartGut is the first sequencing-based clinical microbiome screening test.

SmartGut is the world’s first sequencing-based clinical microbiome screening test based on our patented technology and extensive peer-reviewed research. The test detects beneficial and pathogenic microorganisms associated with gut conditions like irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s Disease.

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Easy-to-use

Easy-to-use sample collection kit, which includes clear, simple instructions and everything you need, including a prepaid return mailer.

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Healthcare provider-ordered

Ordered by a healthcare provider and processed in our CLIA-certified and CAP-accredited lab to give you the confidence to take action.

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Simple and mess-free

Requires only a very small sample of fecal matter from your toilet paper (just enough to tint a cotton swab) that you can collect and return to our lab.

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Advanced

SmartGut includes the detection of microorganisms that can only be detected by DNA sequencing.

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Data-driven

Powered by the world’s largest microbiome database and our proprietary algorithms, SmartGut includes unique, healthy microbiome ranges.

See how SmartGut can help you and your healthcare provider learn more about symptoms from three major conditions

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How SmartGut works

1

Request test

Requesting your test is quick and easy. A few online questions, and you’re done.

2

Healthcare provider reviews request

Your own healthcare provider can approve your test, or we can connect you with an independent healthcare provider in our external clinical care network.

3

Sample at home

In a few business days, your kit will arrive in a discreet package. Clear instructions will tell you how to self sample. It’s fast and private, and takes place in the comfort of your home. After you collect your sample, put it in the prepaid envelope and drop it in the nearest mailbox.*

* Microbes in the mail?! Don’t worry. Your sampling tube contains our stabilization buffer which lyses (or kills) your microbes upon contact. Any potential infectious agent is dead before mailing. You can read more about our stabilization buffer here

Instructions for SmartGut

4

We process

We process in our CLIA-licensed and CAP-accredited laboratory in San Francisco. Once your sample is processed in our lab, we’ll send you a HIPAA-compliant link so you and your healthcare provider can download your test results.

The inside story

Have we mentioned how easy this is?
Collect your sample in less than two minutes.

Your SmartGut collection kit includes everything you need to complete your sample in less than two minutes in the comfort and privacy of your own home.

  • 1Sample tube

    This tube contains a special stabilizing fluid that preserves your sample during its journey to our laboratory.

  • 2Two sterile swabs


    Use these medical swabs to obtain your sample.

  • 3Replacement sample tube

    Use this as a replacement only if you spill or lose your sample tube.

  • 4Sample return bag

    Place your sample in this bag before putting it into the return mailer.

  • 5Return mailer

    Your sample tube and return bag go inside the return mailer. Postage is prepaid by uBiome.

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Did you know? You can monitor your microbiome over time.

Learn much more about your microbiome. Once a month, once a quarter or as recommended by your healthcare provider, you can discover how your microbes change over time.

Detailed clinical report

You’ll receive a detailed report with information on microorganisms associated with lifestyle choices, specific infections and gut conditions. You and your healthcare provider can use this report to gain valuable insight into your gut health that might help to determine a diagnosis.

Infections

The presence of specific pathogenic microorganisms in your microbiome can be associated with illness.

Gut conditions

Your microbiome might include microorganisms associated with conditions such as irritable bowel syndrome, bloating, or other gut symptoms and diagnoses. Find out more about the relationship between your gut conditions and your microbiome.

Metabolic disorders

The gut microbiome composition has been linked with metabolic disorders, including diabetes, obesity, and non-alcoholic fatty liver disease.

Cardiovascular Disease

Your microbiome may potentially include microorganisms associated with cardiovascular disease and atherosclerosis.

Kidney Disease

The gut microbiome composition has been linked with kidney disease including kidney stones and chronic kidney disease.

Diversity score

The SmartGut microbiome diversity score indicates how your microbiome compares to that of healthy participants from the world’s largest microbiome research dataset.

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Symptoms and diagnoses

SmartGut can help you monitor your overall gut health regularly. It detects the microorganisms associated with several common gut symptoms, including:

  • Diarrhea
  • Irritable bowel syndrome (IBS)
  • Inflammatory bowel disease (IBD) including Crohn’s disease and ulcerative colitis
  • Abdominal tenderness
  • Bloating
  • Constipation
  • Flatulence
  • Asymptomatic diverticulosis
  • Obesity
  • Prediabetes
  • Type 2 diabetes
  • Non-alcoholic fatty liver disease
  • Atherosclerosis
  • Cardiovascular disease
  • Kidney stones
  • Chronic kidney disease

I’m a licensed healthcare provider. Can I prescribe SmartGut to my patients?

Yes! Read about the benefits of SmartGut to discover how SmartGut can help you provide better care for your patients. Learn more

How much does SmartGut™ cost?

SmartGut™ is an insurance-reimbursed test ordered by a healthcare provider. uBiome clinical tests are fully or partially covered by most health insurance companies under “out-of-network” healthcare benefits. We have patient assistance programs in place to assist eligible patients with the remaining patient responsibility. You may receive an Explanation of Benefits (EOB) from your insurance company. An EOB is NOT a bill. It is simply informational and shows how your insurance processed the claim for your uBiome service.

FAQs

  • Probiotic Foods: The Good Bugs

    When you think of gut health, your mind may jump straight to the word “probiotic.” This isn’t surprising; a Google Trend Report indicated that consumer demand for probiotics has increased significantly since 2004.

    Additionally, since the mid-1990s, research has suggested that probiotics may “aid digestion and help maintain gut health.”

     

    What are probiotics?

    The World Health Organization defines probiotics as “live microorganisms which when administered in adequate amounts confer a health benefit on the host.”  

    According to the National Center for Complementary and Integrative Health, probiotics may help your body find the proper balance of microorganisms and “stabilize the digestive tract’s barriers against undesirable microorganisms.”

     

    Probiotic Foods

    Probiotics aren’t only available in supplement form. Many delicious foods are naturally full of probiotics!

    Yogurt, for example, is produced when a starter culture of bacteria – usually Streptococcus thermophilus and Lactobacillus bulgaricus –  is added to milk. The bacteria break down the lactose sugars into lactic acid.

    Pickling is a time tested technique for preserving vegetables and fruits. While pickling can involve immersing produce in vinegar to kill all the bacteria, a similar outcome can result from immersing produce in salted water for several weeks. In that briny environment, the Lactobacillus bacteria that naturally occurs on produce like cucumbers have a chance to produce lactic acid, which serves as a preservative.

    Another common category of probiotic-rich foods is fermented foods. Foods ferment when molds, yeasts, or bacteria produce enzymes that break down the food into smaller, simpler compounds. The fermented foods are often abundant in probiotic bacteria, such as Lactobacillus, Bifidobacterium, Pediococcus, and Weisella.

    Probiotic-rich foods include:

    • Yogurt
    • Pickles
    • Sauerkraut
    • Kimchi
    • Kombucha
    • Miso
    • Kvass
    • Cottage cheese
    • Many more!

     

    Curious if the probiotic bacteria in the food you’re eating is making its way to your gut?

    Explorer™ identifies microbes found in the most common probiotic foods and lets you see how your levels of these microbes compare to others who consume these foods.

     

    Use the code UNLEASH at checkout to get 50% off a Gut Explorer kit through the end of February 2019.

    If you’ve used Explorer and have a story to tell, we’d love to hear from you! Share your story on social tagging @ubiome and #UnleashYourExplorer. You’ll be entered for the chance to win 1 Gut Explorer kit each week during February and for the Grand Prize Drawing: a Gut Time Lapse set.*

    *All posts must tag @uBiome and use #UnleashYourExplorer to be counted as a valid entry. The first weekly contest will run Friday 2/1 to Thursday 2/14. Entries must be received by 11:59pm PST on Thursday 2/1. The Grand Prize contest will run Friday 2/1 – Thursday 2/28.  Entries must be received by 11:59 PST on Thursday 2/28 for the Grand Prize. Weekly winners will be announced at 10:00am PST on Friday 2/15. The Grand Prize winner will be announced by 10:00am PST on 3/1/2019.
  • Probiotic Foods: The Good Bugs

    When you think of gut health, your mind may jump straight to the word “probiotic.” This isn’t surprising; a Google Trend Report indicated that consumer demand for probiotics has increased significantly since 2004.

    Additionally, since the mid-1990s, research has suggested that probiotics may “aid digestion and help maintain gut health.”

     

    What are probiotics?

    The World Health Organization defines probiotics as “live microorganisms which when administered in adequate amounts confer a health benefit on the host.”  

    According to the National Center for Complementary and Integrative Health, probiotics may help your body find the proper balance of microorganisms and “stabilize the digestive tract’s barriers against undesirable microorganisms.”

     

    Probiotic Foods

    Probiotics aren’t only available in supplement form. Many delicious foods are naturally full of probiotics!

    Yogurt, for example, is produced when a starter culture of bacteria – usually Streptococcus thermophilus and Lactobacillus bulgaricus –  is added to milk. The bacteria break down the lactose sugars into lactic acid.

    Pickling is a time tested technique for preserving vegetables and fruits. While pickling can involve immersing produce in vinegar to kill all the bacteria, a similar outcome can result from immersing produce in salted water for several weeks. In that briny environment, the Lactobacillus bacteria that naturally occurs on produce like cucumbers have a chance to produce lactic acid, which serves as a preservative.

    Another common category of probiotic-rich foods is fermented foods. Foods ferment when molds, yeasts, or bacteria produce enzymes that break down the food into smaller, simpler compounds. The fermented foods are often abundant in probiotic bacteria, such as Lactobacillus, Bifidobacterium, Pediococcus, and Weisella.

    Probiotic-rich foods include:

    • Yogurt
    • Pickles
    • Sauerkraut
    • Kimchi
    • Kombucha
    • Miso
    • Kvass
    • Cottage cheese
    • Many more!

     

    Curious if the probiotic bacteria in the food you’re eating is making its way to your gut?

    Explorer™ identifies microbes found in the most common probiotic foods and lets you see how your levels of these microbes compare to others who consume these foods.

     

    Use the code UNLEASH at checkout to get 50% off a Gut Explorer kit through the end of February 2019.

    If you’ve used Explorer and have a story to tell, we’d love to hear from you! Share your story on social tagging @ubiome and #UnleashYourExplorer. You’ll be entered for the chance to win 1 Gut Explorer kit each week during February and for the Grand Prize Drawing: a Gut Time Lapse set.*

    *All posts must tag @uBiome and use #UnleashYourExplorer to be counted as a valid entry. The first weekly contest will run Friday 2/1 to Thursday 2/14. Entries must be received by 11:59pm PST on Thursday 2/1. The Grand Prize contest will run Friday 2/1 – Thursday 2/28.  Entries must be received by 11:59 PST on Thursday 2/28 for the Grand Prize. Weekly winners will be announced at 10:00am PST on Friday 2/15. The Grand Prize winner will be announced by 10:00am PST on 3/1/2019.
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Support

Our customer support team is available by email and is happy to answer any questions you have about sampling, results, and more.

uBiome’s social mission

uBiome’s mission is to advance the science of the microbiome and make it useful to people. Through our research with thousands of citizen scientists and dozens of universities, including Harvard, Stanford, UCSF and others, we have gathered millions of data points and built a set of tools that have enabled us to create clinical tests for healthcare providers and patients.

For people

We are committed to empowering people to understand and take greater control of their health. Through our uBiome Explorer kits and our microbiome database – the largest in the world – we give people access to tools to better understand the microbiome.

For science

To advance the science of the microbiome, we work with over 1,000 researchers from around the world at institutions such as Harvard, Stanford, UCSF, University College London, and the National University of Singapore.

For the world

We also work with over 150,000 citizen scientists in more than 80 countries. Our projects include large-scale citizen scientist studies, partnerships with researchers and organizations, and support for underfunded scientific discovery via our $1 million Microbiome Impact Grant Initiative (as part of the White House National Microbiome Initiative).