To sign up for a uBiome account, please choose your product

Hero Image

Learn about your body.

SmartJane™ is the discreet and easy screening test for HPV, STIs, and the balance of vaginal flora.

The inclusive vaginal health check.

SmartJane™ is the first women’s health screening test to simultaneously check multiple conditions – including HPV, STIs and other vaginal factors – all from one sample.

Using our patented precision sequencing™ technology, as well as our proprietary algorithms, the test genotypes 14 high-risk HPV strains, 5 low-risk HPV strains, 4 common STIs (chlamydia, gonorrhea, syphilis, and mycoplasma genitalium). SmartJane also measures 23 other vaginal flora.

SmartJane does not screen for cancer and is not intended to replace traditional Pap smears or well woman visits. SmartJane is only available with a valid lab test order from a healthcare provider.

Why SmartJane?

SmartJane is the world’s first sequencing-based clinical microbiome screening test for vaginal flora, HPV and STIs.

Sample at home, when it’s right for you. Your SmartJane Collection Kit contains everything you’ll need to collect your sample in less than three minutes, in the comfort of your own bathroom.

why icon image

Detects high-risk HPV strains

SmartJane tests for HPV, which is associated with cervical cancer and precancerous cervical lesions1. We detect the two most common strains (HPV-16 and HPV-18), as well as twelve additional strains.

1 Audirac-Chalifour et al., 2016, Lee et al., 2013

 

why icon image

Detects low-risk HPV strains

such as HPV-6 and HPV-11. These strains are responsible for about 90% of genital warts, but they rarely develop into cancer.

 

why icon image

Reveals your flora balance

SmartJane can tell you about your vaginal flora balance. An imbalance is associated with conditions such as bacterial vaginosis (BV), a common vaginal infection2.

Onderdonk et al., 2016, Srinivasan et al., 2012

 

why icon image

Identifies microbial co-factors

Certain bacteria are associated with HPV infection3. SmartJane provides information on these unique co-factors and how they relate to your health.

3 Mitra et al., 2016, Mitra et al., 2015

 

How SmartJane works

1

Request test

Requesting your test is quick and easy. A few online questions, and you’re done.

2

Healthcare provider reviews request

Your own healthcare provider can approve your test, or an independent healthcare provider from an external clinical care network can review your request.

3

Sample at home

In a few business days, your kit will arrive in a discreet package. Clear instructions will tell you how to self-sample. It’s fast and private, and takes place in the comfort of your home.* 

* Microbes in the mail?! Don’t worry. Your sampling tube contains our stabilization buffer which lyses (or kills) your microbes upon contact. Any potential infectious agent is dead before mailing. You can read more about our stabilization buffer here

Instructions for SmartJane

4

We process

After you collect your sample, stick it in the prepaid envelope and drop it in the nearest mailbox. Once it’s processed in our lab, we’ll send you a link so you and your healthcare provider can download your test results.

The inside story

Have we mentioned how easy this is?
Collect your sample in less than two minutes.

  • 1Sample tube

    This tube contains a special stabilizing fluid that preserves your sample during its journey to our laboratory.

  • 2Sterile DNA-free water

    DNA-free water is a special grade of water used to collect microorganisms.

  • 3Two sterile swabs


    Use these to take your sample.

  • 4Replacement sample tube

    Use this as a replacement only if you spill or lose your sample tube.

  • 5Sample return bag

    Place your sample in this bag before putting it into the return mailer.

  • 6Return mailer

    Your sample tube and return bag go inside the return mailer. Postage is prepaid by uBiome.

Under the hood image

Did you know? You can monitor your microbiome.

Learn much more about your microbiome and how it changes over time with regularly analyzed samples or as recommended by your healthcare provider. SmartJane does not screen for cancer and is not intended to replace traditional Pap smears or well woman visits. SmartJane is only available with a valid lab test order from a healthcare provider.

Detailed clinical report

You’ll receive a detailed report with information about your vaginal microbiome – including lactobacillus, HPV, and other sexually transmitted infections. You and your healthcare provider can use this report to gain valuable insight into your vaginal health that might help to determine a diagnosis. SmartJane is friendly to trans and non-binary patients.

HPV screening

Your sample will be checked for the 14 most common high-risk strains of HPV, including HPV-16 and HPV-18 as well as the 5 low-risk strains that can cause genital warts.

Sexually transmitted infections

Your results include screening your sample for four common STIs, chlamydia and gonorrhea.

Vaginal flora balance

Get information about the composition of your vaginal microbiome, and learn how your vaginal microbes may impact overall health and wellness.

Hero Image

Why is HPV testing so important?

 

There are multiple strains of HPV. Those that are considered high-risk are associated with cervical cancer, while low-risk types can cause genital warts. Other types of HPV have no known health consequences.

HPV spreads from person to person by having vaginal, anal, or oral sex with someone who already has the virus, even if they have no symptoms. It’s possible to get HPV after only having sex with just one person in your lifetime, who didn’t know they were infected. What’s more, your infection may not become apparent for years after you had sex with this person.

It is recommended that any individual who is – or has been – sexually active or who may have concerns about the risk of cervical cancer, should be regularly screened for HPV. Even if you have been vaccinated, getting screened can help you have more information about your future risk. For more information, see the NIH National Cancer Institute website.

The SmartJane test does not replace your regular physical exams or standard of care cervical cancer screening. Please make sure to see your healthcare provider regularly.

Half image

Symptoms and diagnoses

  • SmartJane genotypes HPV, tests for STIs, and assesses vaginal flora balance, which may affect the risk of cervicitis, idiopathic infertility, pelvic inflammatory disease, bacterial vaginosis, and aerobic vaginitis.
  • SmartJane compares the levels of 23 microorganisms in your vaginal microbiome to a healthy reference range.
  • SmartJane reviews the significance of the state of your microbiome in relation to 10 health conditions.

Are you a licensed healthcare provider?

Read about the benefits of SmartJane to discover how SmartJane can help you provide better care for patients. SmartJane does not screen for cancer and is not intended to replace traditional Pap smears or well woman visits. SmartJane is only available with a valid lab test order from a healthcare provider.

How much does SmartJane™ cost?

SmartJane™ is an insurance-reimbursed test ordered by a healthcare provider. uBiome clinical tests are fully or partially covered by most health insurance companies under “out-of-network” healthcare benefits. We have patient assistance programs in place to assist eligible patients with the remaining patient responsibility. You may receive an Explanation of Benefits (EOB) from your insurance company. An EOB is NOT a bill. It is simply informational and shows how your insurance processed the claim for your uBiome service.

FAQs

  • Probiotic Foods: The Good Bugs

    When you think of gut health, your mind may jump straight to the word “probiotic.” This isn’t surprising; a Google Trend Report indicated that consumer demand for probiotics has increased significantly since 2004.

    Additionally, since the mid-1990s, research has suggested that probiotics may “aid digestion and help maintain gut health.”

     

    What are probiotics?

    The World Health Organization defines probiotics as “live microorganisms which when administered in adequate amounts confer a health benefit on the host.”  

    According to the National Center for Complementary and Integrative Health, probiotics may help your body find the proper balance of microorganisms and “stabilize the digestive tract’s barriers against undesirable microorganisms.”

     

    Probiotic Foods

    Probiotics aren’t only available in supplement form. Many delicious foods are naturally full of probiotics!

    Yogurt, for example, is produced when a starter culture of bacteria – usually Streptococcus thermophilus and Lactobacillus bulgaricus –  is added to milk. The bacteria break down the lactose sugars into lactic acid.

    Pickling is a time tested technique for preserving vegetables and fruits. While pickling can involve immersing produce in vinegar to kill all the bacteria, a similar outcome can result from immersing produce in salted water for several weeks. In that briny environment, the Lactobacillus bacteria that naturally occurs on produce like cucumbers have a chance to produce lactic acid, which serves as a preservative.

    Another common category of probiotic-rich foods is fermented foods. Foods ferment when molds, yeasts, or bacteria produce enzymes that break down the food into smaller, simpler compounds. The fermented foods are often abundant in probiotic bacteria, such as Lactobacillus, Bifidobacterium, Pediococcus, and Weisella.

    Probiotic-rich foods include:

    • Yogurt
    • Pickles
    • Sauerkraut
    • Kimchi
    • Kombucha
    • Miso
    • Kvass
    • Cottage cheese
    • Many more!

     

    Curious if the probiotic bacteria in the food you’re eating is making its way to your gut?

    Explorer™ identifies microbes found in the most common probiotic foods and lets you see how your levels of these microbes compare to others who consume these foods.

     

    Use the code UNLEASH at checkout to get 50% off a Gut Explorer kit through the end of February 2019.

    If you’ve used Explorer and have a story to tell, we’d love to hear from you! Share your story on social tagging @ubiome and #UnleashYourExplorer. You’ll be entered for the chance to win 1 Gut Explorer kit each week during February and for the Grand Prize Drawing: a Gut Time Lapse set.*

    *All posts must tag @uBiome and use #UnleashYourExplorer to be counted as a valid entry. The first weekly contest will run Friday 2/1 to Thursday 2/14. Entries must be received by 11:59pm PST on Thursday 2/1. The Grand Prize contest will run Friday 2/1 – Thursday 2/28.  Entries must be received by 11:59 PST on Thursday 2/28 for the Grand Prize. Weekly winners will be announced at 10:00am PST on Friday 2/15. The Grand Prize winner will be announced by 10:00am PST on 3/1/2019.
  • Probiotic Foods: The Good Bugs

    When you think of gut health, your mind may jump straight to the word “probiotic.” This isn’t surprising; a Google Trend Report indicated that consumer demand for probiotics has increased significantly since 2004.

    Additionally, since the mid-1990s, research has suggested that probiotics may “aid digestion and help maintain gut health.”

     

    What are probiotics?

    The World Health Organization defines probiotics as “live microorganisms which when administered in adequate amounts confer a health benefit on the host.”  

    According to the National Center for Complementary and Integrative Health, probiotics may help your body find the proper balance of microorganisms and “stabilize the digestive tract’s barriers against undesirable microorganisms.”

     

    Probiotic Foods

    Probiotics aren’t only available in supplement form. Many delicious foods are naturally full of probiotics!

    Yogurt, for example, is produced when a starter culture of bacteria – usually Streptococcus thermophilus and Lactobacillus bulgaricus –  is added to milk. The bacteria break down the lactose sugars into lactic acid.

    Pickling is a time tested technique for preserving vegetables and fruits. While pickling can involve immersing produce in vinegar to kill all the bacteria, a similar outcome can result from immersing produce in salted water for several weeks. In that briny environment, the Lactobacillus bacteria that naturally occurs on produce like cucumbers have a chance to produce lactic acid, which serves as a preservative.

    Another common category of probiotic-rich foods is fermented foods. Foods ferment when molds, yeasts, or bacteria produce enzymes that break down the food into smaller, simpler compounds. The fermented foods are often abundant in probiotic bacteria, such as Lactobacillus, Bifidobacterium, Pediococcus, and Weisella.

    Probiotic-rich foods include:

    • Yogurt
    • Pickles
    • Sauerkraut
    • Kimchi
    • Kombucha
    • Miso
    • Kvass
    • Cottage cheese
    • Many more!

     

    Curious if the probiotic bacteria in the food you’re eating is making its way to your gut?

    Explorer™ identifies microbes found in the most common probiotic foods and lets you see how your levels of these microbes compare to others who consume these foods.

     

    Use the code UNLEASH at checkout to get 50% off a Gut Explorer kit through the end of February 2019.

    If you’ve used Explorer and have a story to tell, we’d love to hear from you! Share your story on social tagging @ubiome and #UnleashYourExplorer. You’ll be entered for the chance to win 1 Gut Explorer kit each week during February and for the Grand Prize Drawing: a Gut Time Lapse set.*

    *All posts must tag @uBiome and use #UnleashYourExplorer to be counted as a valid entry. The first weekly contest will run Friday 2/1 to Thursday 2/14. Entries must be received by 11:59pm PST on Thursday 2/1. The Grand Prize contest will run Friday 2/1 – Thursday 2/28.  Entries must be received by 11:59 PST on Thursday 2/28 for the Grand Prize. Weekly winners will be announced at 10:00am PST on Friday 2/15. The Grand Prize winner will be announced by 10:00am PST on 3/1/2019.
support image

Support

Our customer support team is available by email and is happy to answer any questions you have about sampling, results, and more.

uBiome’s social mission

uBiome’s mission is to advance the science of the microbiome and make it useful to people. Through our research with thousands of citizen scientists and dozens of universities, including Harvard, Stanford, UCSF and others, we have gathered millions of data points and built a set of tools that have enabled us to create clinical tests for healthcare providers and patients.

For people

We are committed to empowering people to understand and take greater control of their health. Through our uBiome Explorer kits and our microbiome database – the largest in the world – we give people access to tools to better understand the microbiome.

For science

To advance the science of the microbiome, we work with over 1,000 researchers from around the world at institutions such as Harvard, Stanford, UCSF, University College London, and the National University of Singapore.

For the world

We also work with over 150,000 citizen scientists in more than 80 countries. Our projects include large-scale citizen scientist studies, partnerships with researchers and organizations, and support for underfunded scientific discovery via our $1 million Microbiome Impact Grant Initiative (as part of the White House National Microbiome Initiative).