Which uBiome product is right for you?

SmartGut

Doctor-ordered gut health test

SmartJane

Doctor-ordered women’s health test

Explorer

Discover your microbiome without the help of a doctor

Who is it for?

Patients with chronic gut conditions such as IBD or IBS, or symptoms such as gas, bloating or diarrhea.

Patients with the desire to, alongside their healthcare provider, learn more about their own vaginal health and how to improve conditions, such as discharges or infections, through lifestyle or diet.

Health and wellness tool to help you better discover how diet and lifestyle affect your microbiome.

Doctor authorization required?

Yes

Yes

No

Where is it available?

US and Canada (other countries coming soon)

US and Canada (other countries coming soon)

203 countries and regions where online payments can be made with a credit card or PayPal

What is the price?

uBiome clinical tests are fully or partially covered by most health insurance companies under “out-of-network” healthcare benefits. We have patient assistance programs in place to assist eligible patients with the remaining patient responsibility.

uBiome clinical tests are fully or partially covered by most health insurance companies under “out-of-network” healthcare benefits. We have patient assistance programs in place to assist eligible patients with the remaining patient responsibility.

From $89 for one site to $399 for five sites.

Targeted at which body site(s)?

Gut microbiome exclusively

Vaginal microbiome

Gut, nose, oral, skin or genital microbiome.

Suitable for other sampling purposes?

SmartGut is solely for adult gut samples.

SmartJane is solely for adult vaginal samples

Yes! Sample kids, pets, home environment, etc.

Any age requirements?

Available to all ages, parental permission needed if under 18.

Available to everyone aged 18 years and older.

Available to all ages, parental permission needed if under 18.

How is sample collected?

Easy self-sampling at home, takes under three minutes.

Easy self-sampling at home, takes under three minutes.

Easy self-sampling at home, takes under three minutes.

What do results show?

Detects beneficial and pathogenic microorganisms associated with specific infections, lifestyle choices, and gut conditions including Inflammatory Bowel Disease (IBD) and irritable bowel syndrome (IBS).

Detects beneficial and pathogenic microorganisms associated with specific infections, such as cervicitis, bacterial vaginosis or vaginitis.

Interactive online tools enable you to explore how your microbiome compares to others, and to monitor yourself over time.

Where does processing take place?

In our San Francisco laboratory, which is CLIA-certified and accredited by the College of American Pathologists (CAP), a standard only achieved by the top 3% of laboratories in the world.

In our San Francisco laboratory, which is CLIA-certified and accredited by the College of American Pathologists (CAP), a standard only achieved by the top 3% of laboratories in the world.

In our San Francisco laboratory, which is CLIA-certified and accredited by the College of American Pathologists (CAP), a standard only achieved by the top 3% of laboratories in the world.

Can you participate in scientific research?

Optionally enables you to anonymously participate in scientific research aimed at advancing understanding of the human microbiome.

Optionally enables you to anonymously participate in scientific research aimed at advancing understanding of the human microbiome.

Optionally enables you to anonymously participate in scientific research aimed at advancing understanding of the human microbiome.

Helping you help patients.

Understand your patient’s condition with greater precision.
Start ordering tests →

SmartGut™ uses precision sequencing™ technology to accurately identify dozens of important species and genera.

SmartGut helps you gain insight into your patients’ gut health. Patients self-sample conveniently at home, then mail samples to the lab. Once testing is complete, we will email you and your patient a HIPAA-compliant link to a PDF. This detailed report shows dozens of microorganisms as well as information on how they relate to gut health.

 

Want to collaborate with us?

Join The Microbiome Innovation Challenge and tell us about your ideas.

SmartGut Resources

Learn more about our company, our SmartGut™ test, the groundbreaking science at uBiome, and how our work is advancing the field of microbial genomics.

To start ordering our clinical tests, create a provider account now. If you have any questions, contact our Clinical Partnerships Team.

 

SmartGut metrics and methods

The uBiome SmartGut screening test includes information on dozens of clinically relevant bacteria and other microorganisms associated with health and disease.

  • 1Safe at ambient temperatures

    SmartGut collection kits include a stabilization buffer, which effectively lyses and kills all microorganisms and preserves the sample DNA for transport at ambient temperatures to our CLIA-certified and CAP-accredited laboratory.

  • 2Precision Sequencing™ technology

    We use patent pending Precision Sequencing™ technology to extract DNA from microorganisms present in a SmartGut sample, allowing us to achieve greater precision in identifying specific test targets. All targeted genes are sequenced using Illumina® Next-Generation sequencing.

  • 3Secure computing cluster

    We run our analysis on a secure, high-performance computing cluster. Once we’ve determined a sample’s taxonomic composition, we compare it to an established healthy reference range that is based on the world’s largest microbiome dataset.

  • 4Taxonomic annotation

    Our bioinformatics pipeline enables us to generate a taxonomic annotation of the dozens of clinically relevant species and genera that may be present in a SmartGut sample. Analysis of SmartGut samples is performed using high-throughput bioinformatics, incorporating phylogenetic algorithms and custom databases specifically developed for microbiome data.

  • 5Extensive literature review

    Our extensive and ongoing review of scientific literature has identified numerous associations between the microorganisms on the SmartGut panel and human health and disease. The SmartGut test report incorporates this information and provides insights into how specific microorganisms may affect your patients.

  • 6High specificity and sensitivity

    On average, the sensitivity, specificity, precision, and negative prediction value for the microorganisms on our target list are 99.0%, 100%, 98.9%, and 100%, for the species, and 97.4%, 100%, 98.5%, and 100% for the genera, respectively. Using advanced DNA sequencing technology, we can achieve much better test metrics than other similar tests.

    The uBiome SmartGut microbiome test can help in understanding the following conditions:

    • Irritable bowel syndrome
    • Inflammatory Bowel Disease including Crohn’s Disease and Ulcerative Colitis
    • Constipation or diarrhea
    • Abdominal tenderness
    • Bloating
    • Flatulence
    • Obesity
    • Diabetes

    World-class science

    With over 50 scientists on our team from universities like UCSF, Stanford, Harvard, UCSD, Cambridge (UK) and Oxford (UK), over 300 scientific papers, and over 100 patents filed (73 published, 6 granted) on our technology, uBiome continues to break new ground scientifically.

    Learn more about our science

    CLIA-licensed and CAP-accredited laboratory in San Francisco

    Your samples are in safe hands with us. Only around 3% of laboratories in the US have the level of accreditation achieved by the uBiome lab, which has been accredited by the College of American Pathologists (CAP) and has received a Clinical Laboratory Improvement Amendments (CLIA) certificate.

    Protecting your privacy

    Your privacy is our top priority. To ensure the confidentiality of your data and your results, we use multiple layers of encryption and the highest levels of computer security. You control your data, and can choose whether or not you consent to having your data anonymized and aggregated into uBiome research studies.

    Scientific research

    Recent partnerships have included those with 1,000 researchers from around the world at institutions such as Harvard, Stanford, UCSF, National University of Singapore, and University College London.

     

    uBiome’s social mission

    uBiome’s mission is to advance the science of the microbiome and make it useful to people. Through our research with thousands of citizen scientists and dozens of universities, including Harvard, Stanford, UCSF and others, we have gathered millions of data points and built a set of tools that have enabled us to create clinical tests for healthcare providers and patients.

    For people

    We are committed to empowering people to understand and take greater control of their health. Through our uBiome Explorer kits and our microbiome database – the largest in the world – we give people access to tools to better understand the microbiome.

    For science

    To advance the science of the microbiome, we work with over 1,000 researchers from around the world at institutions such as Harvard, Stanford, UCSF, University College London, and the National University of Singapore.

    For the world

    We also work with over 150,000 citizen scientists in more than 80 countries. Our projects include large-scale citizen scientist studies, partnerships with researchers and organizations, and support for underfunded scientific discovery via our $1 million Microbiome Impact Grant Initiative (as part of the White House National Microbiome Initiative).